University of California San Francisco

Norah Terrault - 144
Norah
Terrault
MD, MPH

Professor of Clinical Medicine & Surgery
Departments of Medicine & Surgery
Director of Viral Hepatitis Research in Liver Transplantation

Address

513 Parnassus Avenue, MSB, #001
San Francisco, CA 94143
United States

Email: [email protected]
Phone: 415-476-2227
Fax: 415-476-0659

    Biography

    Dr. Norah Terrault is a hepatologist or liver specialist who is recognized internationally for the treatment of viral hepatitis and liver transplantation. Her research includes the study of viral hepatitis and its progression and treatment, especially in liver transplant patients. Her research includes several clinical trials related to preventing and treating chronic hepatitis C and B. Her studies in this area have been presented to the American Association for the Study of Liver Diseases, the leading organization for research in liver disease.

    Terrault completed medical training at the University of Alberta and specialty medical training in Internal Medicine and Gastroenterology at the University of Toronto, both in Canada. Her post-doctoral fellowship in hepatology and viral hepatitis was completed at the University of California, San Francisco while earning a concurrent master's degree in public health from the University of California at Berkeley. She joined the medical staff at UCSF Medical Center in 1997.

    Education

    Institution Degree Dept or School End Date
    University of California, San Francisco Post-Doc Fellow/Scholar Medicine 1995
    University of Alberta M.D. School of Medicine 1987
    University of California, San Francisco Residency
    University of California, San Francisco Clinical Fellowship Gastroenterology

    Board Certifications

    American Board of Internal Medicine, Internal Medicine

    American Board of Internal Medicine, Gastroenterology

    Clinical Expertise

    Alcoholic Liver Disease
    Autoimmune Hepatitis
    Benign Liver Tumors
    Cirrhosis
    Fulminant Hepatic Failure
    Hepatitis B
    Hepatitis C
    Hepatocellular Carcinoma (Liver Cancer)
    Live Donor Liver Transplantation
    Liver Transplantation
    Nonalcoholic Fatty Liver Disease
    Pancreas Transplantation
    Primary Biliary Cirrhosis
    Primary Sclerosing Cholangitis

    Clinical Trials

    1. Related Conditions: Hepatitis C, Viruses, Hepatocellular Cancer, Liver Cancer, Hepatitis, Cirrhosis, Liver Transplant, Hepatitis A| Start Date: | End Date:
    2. Related Conditions: Hepatitis B, Liver Disease, Liver Transplant, Hepatitis A, Hepatitis| Start Date: | End Date:

    Program Affiliations

    UCSF Liver Center

    In the News

    December, 20, 2014 | UCSF Transplant Surgery

    Grants and Funding

    • USC Cirrhosis Clinical Center | NIH | 2021-09-22 - 2026-08-31 | Role: Principal Investigator
    • Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) | NIH | 2002-06-15 - 2024-06-30 | Role: Principal Investigator
    • Hepatitis B Research Network (HBRN): Natural History and Treatment Studies | NIH | 2008-09-30 - 2021-05-31 | Role: Principal Investigator
    • Bay Area Hepatitis C Cooperative Research Center | NIH | 2010-06-15 - 2016-05-31 | Role: Co-Investigator
    • General Clinical Research Center | NIH | 1974-12-01 - 2009-03-31 | Role: Co-Investigator
    • Resistance to Antiviral Therapy in Chronic Hepatitis C | NIH | 2001-08-01 - 2007-04-30 | Role: Principal Investigator

    Research Narrative

    My research focuses on the natural history and treatment of hepatitis C virus (HCV) and hepatitis B virus (HBV), particularly in special populations, including those undergoing liver transplantation. Work in progress addresses the natural history of post-transplant disease and specific therapies to prevent infection or modify HCV and HBV disease progression and loss of grafts from recurrent disease.

    Our virological analyses are focused on characterization of viral mutations that occur in liver transplant recipients receiving antiviral therapies and assessment of the effect of these variant viruses on the natural history and severity of disease post-transplantation. Knowledge of these factors may allow improved organ allocation by identifying subsets of patients with HCV recurrence in liver grafts who would be favorable or unfavorable candidates for retransplantation. 

    Research Interests

    Liver Injury and Repair

    Hepatitis B virus (HBV)

    Hepatitis C virus (HCV)

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 421
    1. Memory T Cell Proliferation before Hepatitis C Virus Therapy Predicts Antiviral Immune Responses and Treatment Success.
      Méndez-Lagares G, Lu D, Chen C, Terrault N, Segal MR, Khalili M, Monto A, Shen H, Manos MM, Lanier LL, Ryan JC, McCune JM, Hartigan-O'Connor DJ| | PubMed
    2. Body mass index trajectories in young adulthood predict non-alcoholic fatty liver disease in middle age: The CARDIA cohort study.
      VanWagner LB, Khan SS, Ning H, Siddique J, Lewis CE, Carr JJ, Vos MB, Speliotes E, Terrault NA, Rinella ME, Lloyd-Jones DM, Allen NB| | PubMed
    3. Safety and efficacy of current direct-acting antiviral regimens in kidney and liver transplant recipients with hepatitis C: Results from the HCV-TARGET study.
      Saxena V, Khungar V, Verna EC, Levitsky J, Brown RS, Hassan MA, Sulkowski MS, O'Leary JG, Koraishy F, Galati JS, Kuo AA, Vainorius M, Akushevich L, Nelson DR, Fried MW, Terrault N, Reddy KR| | PubMed
    4. Short Course of Postoperative Hepatitis B Immunoglobulin Plus Antivirals Prevents Reinfection of Liver Transplant Recipients.
      Radhakrishnan K, Chi A, Quan DJ, Roberts JP, Terrault NA| | PubMed
    5. Alcohol Use and Cardiovascular Disease Risk in Patients With Nonalcoholic Fatty Liver Disease.
      VanWagner LB, Ning H, Allen NB, Ajmera V, Lewis CE, Carr JJ, Lloyd-Jones DM, Terrault NA, Siddique J| | PubMed
    6. Management of hepatitis B in special populations.
      Zhou K, Terrault N| | PubMed
    7. International Liver Transplantation Society Consensus Statement on Hepatitis C Management in Liver Transplant Candidates.
      Terrault NA, McCaughan GW, Curry MP, Gane E, Fagiuoli S, Fung JYY, Agarwal K, Lilly L, Strasser SI, Brown KA, Gadano A, Kwo PY, Burra P, Samuel D, Charlton M, Pessoa MG, Berenguer M| | PubMed
    8. International Liver Transplantation Society Consensus Statement on Hepatitis C Management in Liver Transplant Recipients.
      Terrault NA, Berenguer M, Strasser SI, Gadano A, Lilly L, Samuel D, Kwo PY, Agarwal K, Curry MP, Fagiuoli S, Fung JYY, Gane E, Brown KA, Burra P, Charlton M, Pessoa MG, McCaughan GW| | PubMed
    9. Persistence of Virologic Response after Liver Transplant in Hepatitis C Patients Treated with Ledipasvir / Sofosbuvir Plus Ribavirin Pretransplant.
      Yoshida EM, Kwo P, Agarwal K, Duvoux C, Durand F, Peck-Radosavljevic M, Lilly L, Willems B, Vargas H, Kumar P, Brown RS, Horsmans Y, De-Oertel S, Arterburn S, Dvory-Sobol H, Brainard DM, McHutchison JG, Terrault N, Rizzetto M, MĂĽllhaupt B| | PubMed
    10. Is moderate alcohol use in nonalcoholic fatty liver disease good or bad? A critical review.
      Ajmera VH, Terrault NA, Harrison SA| | PubMed